• Presentations

• Pictures of the workshops

 This EVAN Intensive Training Course will consist of brief research reports, interactive workshops, and practical sessions on the theoretical and technical aspects of the study of growth and the evolution of form. A full-day cultural tour to the famous cave art (rock paintings) site of Niaux (Magdalenian period, circa 14000-13000 BP) will also be organized. During the worshops and practical sessions, form will not be considered as referring only to the external outline and structure of an object. Form will also be presented as representing the mode in which a dynamical anatomical system acts, or manifests itself with a fixed order of processes. Form will also be described as the structure, or pattern, defined by the dynamic arrangement of basic element, parts, within a maturing or an adult organism.

See access and downloadable map at

http://www.ups-tlse.fr

Arrival instructions:

EVAN Training Event – Toulouse 23-27 April 2007

If you are coming from the airport, the easiest is the bus shuttle (all days). It will cist you 6 euros (return ticket) and there is a bus every 20 minutes to (from 7H35 AM to 00H15 AM) and from (from 5H00 AM to 8H20 PM) Toulouse. The duration of the trip is approx. 30 minutes (depending on the traffic). Please stop at the “Allées Jean Jaurès” (orange arrow, first map below) when you arrive in Toulouse. This stop is very close to the Hotels area and within walking distance from our Institute (10 to 15 minutes approx.).

The railway station is indicated by a green arrow in the first map below.

All worshops (except worshop 3) and the evening buffet (please arrive before 7H30 PM) will take place at the Institute : 37 allées Jules Guesde (red arrow, first map below), Faculté de Médecine de Purpan, Salle des Thèses, in the centre of Toulouse. Access via the main entrance. The entrance of the meeting room (“Salle des Thèses”) is at the end of the entrance hall. You will find a sign.

Worshop 3 will be at the IRIT (“Institut de Recherches en Informatique de Toulouse”), Main Campus (see second map below). Please take the bus number 2 or 24 (see map as an attachment; see also second map below) to go there from your hotel (approx. 20-30 minutes in the morning).

If your are coming for the evening buffet on the 23rd of april, please note that the buffet is at 7H00 PM. The doors of the Faculty will close at 8H00 PM. After the buffet, from 8H30, we plan to meet in the “Café des Artistes” - 13, Place de la Daurade. This bar is very close (5-10 minutes walking) to the “Esquirol” metro station (blue arrow on the first map below), in the small square called “La Daurade”, in the bank of the Garonne river. Everyone in Toulouse knows that square : just ask in the street if you get lost between “Esquirol” station and the square.

Niaux tour (25^th) : Our bus will depart from the Institute (37 allées Jules Guesde at 8H00 AM). The visit (at 11H15 AM) will be in english. It may be cold inside the cave at this time.

If you get lost, you can reach me (from France) at 06 78 27 93 78.

Red arrow : Our Institute (39 allées Jules Guesde), Main venue (all worshops except worshop 3) of the meeting incl. welcome buffet (23rd at 7H00 PM), close to the “Grand Rond” (Big Circle) and the Museum of Natural History.

Blue arrow “Esquirol” : Closer metro station (from the Institute)

Orange arrow “Allées Jean Jaurés” : Closer bus stop (from the Hotels area and Institute) to and from the airport (approx. 30 minutes) - Green arrow : Railway station (Gare Matabiau) - Red dotted circle : Hotels area

Green arrow : Main entrance of the Institut de Recherche en Informatique de Toulouse (IRIT), venue of worshop 3

Orange arrow : Main Administrative Building (“Administration”)

Red dotted circle : Bus 24 (from the Institute & Hotels area to the Main Campus)

Blue dotted circle : Bus 2 (from the Hotels area to the Main Campus.

Map of bus & Metro:

DETAILED SCHEDULE

Techniques for quantification of growth and evolution of form

Université Paul Sabatier, Toulouse, France

April 24-27, 2007

An EVAN Consortium Intensive Training Course

Co-sponsored by the :

The Department of Biological Anthropology in the Paul Sabatier University, Toulouse (UNTO) is part of one of the two Faculties of Medicine in Toulouse (Purpan). UNTO comprises a mixture of medical doctors and scientists specialising in forensics, genetics, odontology and palaeoanthropology. UNTO applies medical imaging, nanometrology, visualization, and modelling, for training in the study of human evolution, forensic medicine and orthodontics.

This EVAN Intensive Training Course will consist of brief research reports, interactive workshops, and practical sessions on the theoretical and technical aspects of the study of growth and the evolution of form. A full-day cultural tour to the famous cave art (rock paintings) site of Niaux (Magdalenian period, circa 14000-13000 BP) will also be organized.

During the worshops and practical sessions, form will not be considered as referring only to the external outline and structure of an object. Form will also be presented as representing the mode in which a dynamical anatomical system acts, or manifests itself with a fixed order of processes. Form will also be described as the structure, or pattern, defined by the dynamic arrangement of basic element, parts, within a maturing or an adult organism.

HOSTS

Professor José Braga (Laboratoire d’Anthropobiologie)

Professor Norbert Telmon (Laboratoire d’Anthropobiologie)

Professor Jean-Pierre Jessel (Institut de Recherche en Informatique de Toulouse)

SCIENTIFIC SESSIONS: TWO MAIN VENUES IN TOULOUSE

1 – Faculté de Médecine de Purpan - 37 allés Jules Guesde http://plan.toulouse.fr/

2 – Institut de Recherches en Informatique de Toulouse - 118, Route de Narbonne

(main campus of the Université Paul Sabatier, south of Toulouse)

See access and downloadable map at

http://www.ups-tlse.fr

WORKSHOP 1 - QUANTIFICATION OF SKELETAL GROWTH.

THE SPECIFIC DEMANDS OF FORENSIC PRACTISE.

APRIL 24TH, TUESDAY, MORNING (9H15 - 12H45 AM)

VENUE : FACULTE DE MEDECINE DE PURPAN - 37 ALLES JULES GUESDE

INSTRUCTORS

- FABRICE DEDOUIT, M.D.; DEPARTMENT OF FORENSIC MEDICINE AND FORENSIC PATHOLOGY; DEPARTMENT OF RADIOLOGY; TOULOUSE, FRANCE.

fabded2@hotmail.com

- YANN HEUZE, PH.D.; RADIOLOGIE II MEDIZINISCHE UNIVERSITÄT; ANICHSTRAßE 35, 6020 INNSBRUCK, AUSTRIA.

heuze@cict.fr

http://www.evan.at/Members/yannheuze/Yann_Heuze

- JOSE BRAGA, PH.D., PR.; LABORATOIRE D’ANTHROPOBIOLOGIE, FRE 2960 CNRS ; 39 ALLEES JULES GUESDE, UNIVERSITE PAUL SABATIER ; TOULOUSE, FRANCE.

braga@cict.fr

Educational objectives:

Attendees will gain an overview of current issues and practices in forensic medicine concerning the radiological skeletal and dental and age assessment. They will have the opportunity to be trained with techniques and softwares allowing individual skeletal and dental age assessment.

Program description:

The different backgrounds concerning individual age determination of individuals will be first explained. Prior to radiological examination, many points have to be specified. Concerning radiological skeletal and dental age assessment, important points of growth and development will be introduced.

The different radiological techniques of skeletal age determination will be detailed. The chronological and morphological methods will be presented. Some specifics methods of bone assessment which may be useful for everyday forensic practise will be detailed. The different anatomical sites which have an interest will be presented: namely the elbow, the hand, the wrist and the clavicle. Three specific softwares which are used in forensic medicine for bone age assessment will be practically presented: Maturos, Adagos, Logaetos. A training based on some real forensic cases will be performed by attendees by using these softwares.

Attendees will be trained into radiological non-adult dental age assessment. It will be shown that, in the case of Bayesian non-adult predictions and contrary to age estimation techniques based on regression equations, a better quality does not depend on age.

Attendees will also be trained into pediatric skeletal age assessment using computed tomography and the centroid size of the face derived from the three-dimensional coordinates of anatomical landmarks. It will be shown that some methods that can be applicable from early postnatal age to the end of adolescence with a satisfactory accuracy independent of age and even a better accuracy with greater age.

Knowledge level required: basic.

Bring your own laptop, whenever possible.

WORKSHOP 2 - ASSESSING DENTAL GROWTH SEQUENCES : A MACROSCOPIC/MICROSCOPIC PERSPECTIVE.

USE AND OPERATION OF A PORTABLE OPTICAL PROFILOMETER.

APRIL 24TH, TUESDAY, AFTERNOON (2H00 - 4H15 PM)

VENUE : FACULTE DE MEDECINE DE PURPAN - 37 ALLES JULES GUESDE

INSTRUCTORS

- JOSE BRAGA, PH.D., PR.; LABORATOIRE D’ANTHROPOBIOLOGIE, 39 ALLEES JULES GUESDE, UNIVERSITE PAUL SABATIER ; TOULOUSE, FRANCE.

braga@cict.fr

- TIJANI GHARBI, PH.D., PR. & JAIME MENESE, PH.D., PR. ; DEPARTEMENT D'OPTIQUE P.M. DUFFIEUX ; FEMTO-ST UMR CNRS 6174, UNIVERSITE DE FRANCHE COMTE ; 25030 CEDEX BESANÇON, FRANCE.

tijani.gharbi@univ-fcomte.fr

http://www.femto-st.fr/fr/contact/fiche_personne.php?id=394

Educational objectives:

Attendees will gain an overview of analytical approaches to quantify variability in sequences of key events during development, independent of chronological age. The example of sequences of development of permanent teeth at the macroscopic and microscopic levels will be detailed in order to explain why an integrative analysis of developmental sequences is a critical issue for the future. Indeed, interactions between growing anatomical elements may also contain some information which enables developmental or evolutionary information to be uncovered.

Program description:

During the first part of this workshop, we will describe an analytical approach to provide a comprehensive description of the complex interactions that exist between the growing permanent mandibular teeth (excluding the third molars), and to quantify variability in sequences of key events during crown and root formation. This method integrates the fundamental concept of modularity and rejects the old statistical fallacy of analyzing data on the assumption that it contains no information beyond that revealed on a tooth-by-tooth analysis. This method does not need to be hedged with age assessments of unknown accuracy and reliability levels (particularly in fossils), or the assumption of independence between growing teeth.

The second part of this worshop will consist of the presentation of a portable optical profilometer for measuring tooth crown surfaces and allowing automatic perikymata, hypoplasia counts. This optical device was created for the longitudinal study of sequences of dental crown formation. The first step of this kind of analysis consists in matching patterns of hypoplasia and perikymata spacing between sequences from different teeth in the same individual.

Knowledge level required: basic.

WORKSHOP 4 – QUANTIFICATION OF FORM, PART 1.

APRIL 24TH, TUESDAY, AFTERNOON (4H30 - 5H30 PM)

VENUE : FACULTE DE MEDECINE DE PURPAN - 37 ALLES JULES GUESDE

Worshop 4 is scheduled in the afternoon of the 26^{th of April. However, Professor Gautam Dasgupta cannot be in Toulouse on that day. Consequently, his presentation which constitutes part of Workshop 4, is scheduled just after Workshop 2.}

INSTRUCTOR

GAUTAM DASGUPTA, PH.D., PR.; Civil Engineering and Engineering Mechanics, Columbia University, Mail Code 4709, New York, NY 10027-6699, USA.

gd18@columbia.edu

http://www.columbia.edu/~gd18/

Educational objectives:

Attendees will gain an overview of boundary element shape analysis (based on kinematics) and the analysis of Deformation and strength of thin curved surfaces.

Knowledge level required: basic.

WORKSHOP 3 – THREE-DIMENSIONAL VISUALIZATION AND ANALYSIS OF SURFACE AND CT DATA.

APRIL 26TH, THURSDAY, MORNING (9H30 - 11H30 PM)

VENUE : INSTITUT DE RECHERCHES EN INFORMATIQUE DE TOULOUSE - 118, ROUTE DE NARBONNE (MAIN CAMPUS OF THE UNIVERSITE PAUL SABATIER, SOUTH OF TOULOUSE)

INSTRUCTORS

- JEAN-PIERRE JESSEL, PH.D., PR; IRIT, UNIVERSITE PAUL SABATIER, 118 ROUTE DE NARBONNE, 31062 TOULOUSE CEDEX 9, FRANCE.

Jean-Pierre.Jessel@irit.fr

http://www.irit.fr/~Jean-Pierre.Jessel

- JOSE BRAGA, PH.D., PR.; LABORATOIRE D’ANTHROPOBIOLOGIE, FRE 2960 CNRS ; 39 ALLEES JULES GUESDE, UNIVERSITE PAUL SABATIER ; TOULOUSE, FRANCE.

braga@cict.fr

Educational objectives:

Attendees will gain an overview of tools to deal with visual virtual objects in archaeological and palaeoanthropogical contexts, up to give them, by creation or enhancement, elements allowing to adapt their use according to user features, applications.

Program description:

Visual objects are central in many research activities to allow to create them, edit them, to give them knowledge, to manipulate then thanks to interaction capabilities and to share them through networked environment. The VORTEX group at the "Institut de Recherche en Informatique de Toulouse" (IRIT) aims to form a dynamic group working on visual objects. Their research efforts on visual objects, real or virtual, span a wide range of: still images, videos, 2D and 3D scenes etc.

The worshop will consist of two parts. After a short presentation (first part), the second part will consist on operations of virtual environments. Two groups of 8 participants will be created to see two examples:

- A visit of two virtual caves from France (Tautavel and Gargas) – 30 minutes.

- A µ-computed tomographic analysis of the dental developmental sequence of SK 63, a robust australopithecine from Swartkrans, South Africa – 30 minutes.

Knowledge level required: basic.

WORKSHOP 4 – QUANTIFICATION OF FORM, PART 2.

LANDMARK-BASED ANALYSIS OF SHAPE AND COMPARISON OF GROWTH PATTERNS. FINITE ELEMENT ANALYSIS.

APRIL 26TH, THURSDAY, AFTERNOON (2H00 - 5H30 PM)

VENUE : FACULTE DE MEDECINE DE PURPAN - 37 ALLES JULES GUESDE

INSTRUCTORS

- JOAN T. RICHTSMEIER, PH.D., PR.; DEPARTMENT OF ANTHROPOLOGY, THE PENNSYLVANIA STATE UNIVERSITY; 409 CARPENTER BUILDING, UNIVERSITY PARK, PA, USA.

jta10@psu.edu

http:/getahead.psu.edu

- JOSE MANUEL GARCIA AZNAR, PH.D., PR.; MECHANICAL ENGINEERING DEPT. (DEPTO. INGENIERIA MECANICA), UNIVERSITY OF ZARAGOZA, MARIA DE LUNA 7, CAMPUS RIO EBRO, EDIFICIO "AGUSTIN DE BETANCOURT" 50018 - ZARAGOZA – SPAIN.

jmgaraz@unizar.es

Educational objectives:

The goal of this presentation is to provide an understanding of specific issues that are ignored in morphometrics and to introduce an approach that recognizes the limitations of landmark-based analyses.

Program description:

Professor Joan Richtsmeier will begin by discussing morphometric methods focusing on some of the properties that they hold in common as well as some problems. She will introduce the method Euclidean Distance Matrix Analysis (EDMA) and provide a comparative analysis of form and growth in the mandibles of laboratory mice. The Ts65Dn mouse is an established experimental model for Down syndrome, a human condition in which three copies of human chromosome 21 are present. The Ts65Dn mouse has three copies of the genes on a segment of mouse chromosome 16 which correspond closely in order and identity to those on human chromosome 21. Professor Joan Richtsmeier and others have demonstrated that Ts65Dn mice express a number of features with direct parallels to Down syndrome including precise anatomical changes affecting size and shape of the skull that are analogous to those in Down syndrome. She will use EDMA to test the null hypothesis of similarity in mandibular shape between the two groups of mice, and growth analysis component of EDMA to test the null hypothesis of similarity in mandibular growth patterns. Examination of the results will provide 1) specific data on how the mandibles of trisomic and normal mice differ from one another at the day of birth and in adults, as well as information pertaining to how differences in growth patterns contribute to observed shape difference in adult mandibles, and 2) an example of how EDMA can be applied in the study of biological shape and shape change. Software, publications, landmarking tutorials presented in this first part are available from the Richtsmeier lab website: http:/getahead.psu.edu

In the second part of worshop 4, Professor Garcia Aznar will present the basic concepts of finite element analysis with an example.

Knowledge level required: basic.

Bring your own laptop, whenever possible.

WORKSHOP 5 – QUANTIFICATION OF FORM, PART 3.

THE AXIS OF INERTIA : A MATHEMATICAL TOOL TO CHARACTERIZE THE 3D GEOMETRY OF ANATOMICAL OBJECTS.

MORPHOMETRIC APPROACH OF MANDIBULAR GROWTH AND DEVELOPMENT. WHAT ABOUT SEXUAL DIMORPHISM?

APRIL 27TH, FRIDAY, MORNING (9H30 - 11H30 PM)

INSTRUCTORS

- JACQUES TREIL, M.D.; LABORATOIRE D’ANTHROPOBIOLOGIE, FRE 2960 CNRS ; 39 ALLEES JULES GUESDE, UNIVERSITE PAUL SABATIER ; TOULOUSE, FRANCE.

jtreil@free.fr

- MICHAEL COQUERELLE; UNIVERSITY OF VIENNA, INSTITUT FÜR ANTHROPOLOGY, AUSTRIA; DENTAL SCHOOL OF ATHENS AND D HAL SOFWARE, GREECE; UNIVERSITY OF TOULOUSE 3, FRE 2960 C.N.R.S, FRANCE

michael.coquerelle@tiscali.fr

http://www.evan.at/Members/fellows/employed-fellows

Educational objectives:

Attendees will first gain an overview of the axis of inertia, a tool allowing a relevant geometrical representation of an object, through the quantification of its geometrical dispersion and shape. Examples and applications will be presented.

Program description:

Dr Jacques Treil will present his use of the axis of inertia led us to characterize the relationships of teeth and dental arches and the relationships of dental arches with the maxillo-facial frame. The issue here is to characterize the 3D geometry of discrete anatomical objects as tooth or groups of teeth. These discrete anatomical objects are composed of voxels that are generally non cubic parallelepiped. To simplify the calculation, each parallelepiped is characterized by the values of the Cartesian coordinates, X, Y and Z at its center of gravity. This allows the object to be represented as a cloud of points. The 3D geometry of the object is itself characterized by the dispersion of the points of the cloud, a value that is usually represented by the "matrix of dispersion". The dispersion of the points of the cloud is characterized by the calculation of the principal components axes, which is the statistical approach, or by the calculation of the axes of inertia, which is the physical approach, using the matrix of dispersion. These axes, which are characteristic of the geometry of the object, define a trihedron; the principal axis is the longest; the secondary axis is the second longest; and third axis is the shortest. Their intersection is located at the level of the center of gravity of the object.

Another example will be provided by Michael Coquerelle. His presentation will begin with a concise background about sexual dimorphism in juvenile modern human mandible from a review of some works led since Loth and Henneberg’s studies (2001). Some results from various approaches (visual Vs geometric morphometric) will be shown. Nonetheless, some questions stay in open way due to, firstly, some material lack and, secondly, non-consideration of some parameters. Michael Coquerelle will present a forthcoming study on an original approach of the mandibular morphometry throughout the ontogeny in extant hominoids in which dental development will be taken into account.

Knowledge level required: basic.

PAYMENT

Registration fee (obligatory): 120 EUR

(To Be Paid to "Anthropologies en Midi-Pyrénées").

Includes soft drinks, coffee (9H AM, 10H30 AM and 3H PM), lunch snacks (12H30 PM), during the 24th, 26th and 27th of April.

Each evening dinner will cost additional 30 EUR/participant. If you wish to participate to an evening dinner, please tick the corresponding box above and add 30 EUR/per dinner to your registration payment.

To guarantee your booking for the Training Course, the Registration fee should be paid before the 23rd of March 2007 via bank transfer

to:

Anthropologies en Midi-Pyrénées, Faculté de Médecine de Purpan

Société Générale

IBAN FR76 30003 02110 00037269921 21

BIC (SWIFT-CODE) SOGEFRPP

Please enter "EVAN WORKSHOP - Participant’s Name" in Transfer Details

LIST OF HOTELS

Please find a selection of hotels in Toulouse. Please select a place to stay and book directly well in advance.

Hôtel du Taur

2 rue du Taur, 31000 Toulouse

Tel. 33 5 61 21 17 54 – Fax 33 5 61 13 78 41

contact@hotel-du-taur.com

- www.hotel-du-taur.com

Hôtel Albert 1^er

^- 8 rue Rivals, 31000 Toulouse

Tel. 33 5 61 12 17 91 – Fax 33 5 61 21 09 64

toulouse@hotel-albert1.com

www.hotel-albert1.com

Hôtel Ours Blanc - www.hotel-oursblanc.com

- 2 rue Victor Hugo, 31000 Toulouse

Tel. 33 5 61 21 62 40 - Fax 33 5 61 23 62 34

wilson@hotel-oursblanc.com

-25 place Victor Hugo, 31000 Toulouse

Tel. 33 5 61 23 14 55 - Fax 33 5 61 21 92 01

victorhugo@hotel-oursblanc.cpm

- 2 rue Porte Sardane, 31000 Toulouse

Tel. 33 5 61 21 25 94 - Fax 33 5 61 23 96 27

centre@hotel-oursblanc.com

Hôtel Wilson Square

12 rue d’Austerlitz, 31000 Toulouse

Tel. 33 5 61 21 67 57 – Fax 33 5 61 21 16 23

contact@hotel-wilson.com

- www.hotel-wilson.com